منابع مشابه
Two cases of fatal zopiclone overdose.
Two cases of death due to the ingestion of zopiclone are presented. Quantitative determinations of zopiclone yielded 1.4-3.9 mg/L in the blood, 0.81 and 8.7 mg/kg in the liver, and 13.5 and 133 mg in the stomach contents. Drug concentrations were interpreted relative to the case findings, published data, and a limited evaluation of therapeutic concentrations found in two cases of therapeutic zo...
متن کاملReversal of a Suspected Paradoxical Reaction to Zopiclone with Flumazenil
We describe the care for an elderly woman who was admitted to the intensive care unit (ICU) to receive noninvasive ventilation for acute exacerbation of chronic obstructive pulmonary disease. After administration of the sleeping pill zopiclone, a nonbenzodiazepine receptor agonist (NBRA), the patient became agitated and was confused, a possible paradoxical reaction to benzodiazepines. These sym...
متن کاملEFFICACY OF FLUMAZENIL IN THE MANAGEMENT OF BENZODIAZEPINE OVERDOSE
Benzodiazepine overdose is the most commonly encountered drug overdose in Iran. It has been reported by many authors that flumazenil possesses highly specific antagonistic activity on central benzodiazepine receptors. We conducted a prospective study on 150 patients brought to the toxicology emergency ward in Loghman-Hakim hospital with benzodiazepine overdose to assess the efficacy of flu...
متن کاملefficacy of flumazenil in the management of benzodiazepine overdose
benzodiazepine overdose is the most commonly encountered drug overdose in iran. it has been reported by many authors that flumazenil possesses highly specific antagonistic activity on central benzodiazepine receptors. we conducted a prospective study on 150 patients brought to the toxicology emergency ward in loghman-hakim hospital with benzodiazepine overdose to assess the efficacy of flumazen...
متن کاملLipid rescue of massive verapamil overdose: a case report
INTRODUCTION Massive intentional verapamil overdose is a toxic ingestion which can cause multiorgan system failure and has no currently known antidote. CASE PRESENTATION The patient is a 41-year-old Caucasian woman who ingested 19.2 g of sustained release verapamil in a suicide attempt. Our patient became hypotensive requiring three high-dose vasopressors to maintain arterial pressure. She al...
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ژورنال
عنوان ژورنال: Canadian Medical Association Journal
سال: 2017
ISSN: 0820-3946,1488-2329
DOI: 10.1503/cmaj.732933